Unfortunately, anti-HIV drugs can lose their effectiveness over time. The virus can stop responding to the active ingredients and begin to replicate in the body again. When this happens, we say that the virus has developed resistance.
If the treatment is no longer effective, the amount of virus in the body (viral load) begins to rise again and HIV can once again damage the immune system. This is called treatment failure. In this case, a new combination of drugs must be used.
As there are many different medications to fight HIV today, this is usually possible. On the other hand, there is not an unlimited number of possibilities. The development of resistance should be avoided as much as possible.
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